They have a better flow rate and better filtration efficiency than normal syringe filters. It is used for samples that are hard to filter Hydrophilic material; it is recommended for filtration of aqueous or organic/aqueous medium polar liquids Commonly used for general laboratory filtration and filtration of HPLC and GC samples prior to injection Filtration of aqueous and organic-aqueous polar medium liquids Dissolution sample analysis Suitable for use with high pH samples It requires less hand force. The unique pre-filter layer allows high particulate samples to be filtered with less hand force.